STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
AFZ08032.1Succinate--CoA ligase (ADP-forming); PFAM: CoA binding domain; TIGRFAM: succinyl-CoA synthetase, alpha subunit; COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR003781:IPR005811; KEGG: npu:Npun_F5184 CoA-binding domain-containing protein; PFAM: CoA-binding; ATP-citrate lyase/succinyl-CoA ligase; PRIAM: Succinate--CoA ligase (ADP-forming); SMART: CoA-binding; SPTR: Succinyl-CoA synthetase (ADP-forming) alpha subunit. (298 aa)    
Predicted Functional Partners:
AFZ08031.1
Succinate--CoA ligase (ADP-forming); PFAM: ATP-grasp domain; COGs: COG0045 Succinyl-CoA synthetase beta subunit; InterPro IPR013650:IPR005811; KEGG: ter:Tery_2750 succinyl-CoA synthetase (ADP-forming) beta subunit; PFAM: ATP-grasp fold, succinyl-CoA synthetase-type; ATP-citrate lyase/succinyl-CoA ligase; PRIAM: Succinate--CoA ligase (ADP-forming); SPTR: Succinyl-CoA synthetase (ADP-forming) beta subunit.
 0.999
AFZ07714.1
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR004489; KEGG: ter:Tery_3726 succinate dehydrogenase iron-sulfur subunit; PRIAM: Succinate dehydrogenase; SPTR: Succinate dehydrogenase iron-sulfur subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein.
 0.992
AFZ05340.1
PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunitGram-negative/mitochondrial subgroup; COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR004112:IPR014006; KEGG: npu:Npun_R2767 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase (ubiquinone); SPTR: Succinate dehydrogenase flavoprotein subunit; TIGRFAM: Succinat [...]
 0.988
AFZ10268.1
Dihydrolipoyllysine-residue acetyltransferase; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: ana:alr3606 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; E3 binding; Biotin/lipoyl attachment; PRIAM: Dihydrolipoylly [...]
 
 0.959
AFZ05962.1
NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019554:IPR019575; KEGG: cyj:Cyan7822_3471 NADH dehydrogenase; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (qui [...]
  
 
 0.957
AFZ05971.1
Pyruvate ferredoxin/flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
  
 
 0.932
AFZ06680.1
Succinate dehydrogenase subunit C; PFAM: Cysteine-rich domain; COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: ter:Tery_0453 succinate dehydrogenase subunit C; PFAM: Cysteine-rich domain; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: Succinate dehydrogenase subunit C.
  
  
 0.923
AFZ09625.1
PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR015590:IPR001670; KEGG: cyc:PCC7424_3674 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type; Aldehyde dehydrogenase domain; PRIAM: Acetaldehyde dehydrogenase (acetylating); SPTR: Alcohol dehydrogenase, iron-containing family; alcohol dehydrogenase AdhE; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.895
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 
 0.868
AFZ07705.1
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.838
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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