STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ08057.1PFAM: Hsp70 protein; COGs: COG0443 Molecular chaperone; InterPro IPR013126; KEGG: ava:Ava_0572 heat shock protein HSP70; PFAM: Heat shock protein 70; SPTR: Heat shock protein 70. (529 aa)    
Predicted Functional Partners:
AFZ10292.1
Helix-turn-helix domain protein; PFAM: Helix-turn-helix; InterPro IPR001387; KEGG: ter:Tery_0919 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Putative uncharacterized protein.
 
 
 0.891
dnaJ
Chaperone protein dnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 0.889
AFZ10082.1
PFAM: DnaJ C terminal region; DnaJ domain; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623:IPR002939; KEGG: ter:Tery_4013 chaperone DnaJ-like; PFAM: Chaperone DnaJ, C-terminal; Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Heat shock protein DnaJ-like protein (Modular protein).
  
 0.888
AFZ08319.1
ATP-binding region ATPase domain protein; Molecular chaperone. Has ATPase activity.
   
 0.878
AFZ06928.1
Heat shock protein DnaJ domain protein; PFAM: DnaJ C terminal region; DnaJ domain; COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623:IPR002939; KEGG: ter:Tery_4397 heat shock protein DnaJ-like; PFAM: Heat shock protein DnaJ, N-terminal; Chaperone DnaJ, C-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Heat shock protein DnaJ-like.
  
 0.875
AFZ09385.1
PFAM: DnaJ domain; InterPro IPR001623; KEGG: ter:Tery_5067 heat shock protein DnaJ-like; PFAM: Heat shock protein DnaJ, N-terminal; SPTR: Heat shock protein DnaJ-like.
  
 0.825
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
 
 0.783
AFZ08168.1
KEGG: cyn:Cyan7425_4103 hypothetical protein; SPTR: Putative uncharacterized protein.
 
 
 0.779
AFZ08751.1
PFAM: Protein of unknown function (DUF1257); InterPro IPR009666; KEGG: ava:Ava_4766 hypothetical protein; PFAM: Uncharacterised protein family Ycf35; SPTR: Putative uncharacterized protein.
  
     0.769
AFZ07671.1
PFAM: Protein of unknown function (DUF1257); InterPro IPR009666; KEGG: ter:Tery_2578 hypothetical protein; PFAM: Uncharacterised protein family Ycf35; SPTR: Putative uncharacterized protein.
  
     0.759
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.