STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ08125.1PFAM: 3-dehydroquinate synthase; COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR002658; KEGG: npu:Npun_R5600 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase AroB; PRIAM: 3-dehydroquinate synthase; SPTR: Similar to tr|A0YMN3|A0YMN3_9CYAN 3-dehydroquinate synthase. (412 aa)    
Predicted Functional Partners:
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
  
 0.980
AFZ08127.1
ATP-grasp fold domain protein, DUF201-type; PFAM: ATP-grasp domain; COGs: COG3919 ATP-grasp protein; InterPro IPR003806; KEGG: ava:Ava_3856 hypothetical protein; PFAM: ATP-grasp fold, DUF201-type; SPTR: Similar to tr|Q3M6C5|Q3M6C5_ANAVT ATP-grasp enzyme-like.
   
 0.977
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
 0.963
AFZ08126.1
PFAM: O-methyltransferase; COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: cyc:PCC7424_4982 O-methyltransferase family 3; PFAM: O-methyltransferase, family 3; PRIAM: Caffeoyl-CoA O-methyltransferase; SPTR: Similar to tr|Q4C7D6|Q4C7D6_CROWT Caffeoyl-CoA O-methyltransferase.
   
 0.926
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.900
AFZ08128.1
PFAM: D-ala D-ala ligase C-terminus; COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR011095; KEGG: npu:Npun_F5597 D-alanine--D-alanine ligase domain-containing protein; PFAM: D-alanine--D-alanine ligase, C-terminal; PRIAM: D-alanine--D-alanine ligase; SPTR: Genome sequencing data, contig C317.
 
   
 0.809
AFZ05148.1
3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006268:IPR006218; KEGG: ter:Tery_0171 3-deoxy-7-phosphoheptulonate synthase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2.
 
  
 0.775
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
 0.749
AFZ08496.1
Arogenate dehydrogenase (NADP); PFAM: Prephenate dehydrogenase; COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: ava:Ava_4397 arogenate dehydrogenase; PFAM: Prephenate dehydrogenase; PRIAM: Prephenate dehydrogenase; SPTR: Arogenate dehydrogenase.
 
  
 0.630
AFZ08270.1
Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
  
  
 0.516
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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