STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (349 aa)    
Predicted Functional Partners:
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
 0.916
AFZ09543.1
Farnesyltranstransferase; PFAM: Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: ter:Tery_4173 farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; PRIAM: Farnesyltranstransferase; SPTR: Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.913
AFZ09905.1
Protein of unknown function UPF0047; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme; COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: npu:Npun_F0586 hypothetical protein; PFAM: Uncharacterised protein family UPF0047; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0047.
      0.565
AFZ08248.1
3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short chain dehydrogenase; COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002198; KEGG: ava:Ava_4780 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: Putative uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.480
AFZ08249.1
PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; COGs: COG1062 Zn-dependent alcohol dehydrogenase class III; InterPro IPR020843:IPR013154:IPR013149:IPR014183; KEGG: amr:AM1_2463 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase GroES-like; SMART: Polyketide synthase, enoylreductase; SPTR: Zinc-binding alcohol dehydrogenase; TIGRFAM: Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alc [...]
  
  
 0.467
AFZ08246.1
PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type; signal peptide peptidase SppA, 67K type; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR002142:IPR004634:IPR004635; KEGG: ter:Tery_1590 signal peptide peptidase A; PFAM: Peptidase S49; SPTR: Signal peptide peptidase A; TIGRFAM: Peptidase S49, protease IV; Peptidase S49, SppA.
       0.461
AFZ05971.1
Pyruvate ferredoxin/flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
     
 0.452
AFZ05433.1
PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR002872:IPR015590:IPR005932; KEGG: ter:Tery_3446 L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde dehydrogenase domain; Proline dehydrogenase; SPTR: L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase; TIGRFAM: Delta-1-pyrroline-5-carboxylate dehydrogenase 2; Belongs to the aldehyde dehydrogenase family.
  
  
 0.447
AFZ10336.1
Serine--glyoxylate transaminase; PFAM: Aminotransferase class-V; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: cyn:Cyan7425_0945 serine--pyruvate transaminase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Serine--glyoxylate transaminase; SPTR: Serine--glyoxylate transaminase.
  
 0.406
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.