STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ08345.1Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: npu:Npun_R0622 hypothetical protein; PFAM: Class II aldolase/adducin, N-terminal; SPTR: Putative uncharacterized protein. (257 aa)    
Predicted Functional Partners:
AFZ09434.1
PFAM: Taurine catabolism dioxygenase TauD, TfdA family; InterPro IPR003819; KEGG: npu:Npun_R3451 taurine catabolism dioxygenase TauD/TfdA; PFAM: Taurine catabolism dioxygenase TauD/TfdA; SPTR: Putative uncharacterized protein.
      0.779
AFZ08344.1
KEGG: gvi:glr3989 hypothetical protein; SPTR: Glr3989 protein.
       0.590
AFZ04899.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  
 0.533
AFZ05253.1
HAD-superfamily hydrolase, subfamily IB (PSPase-like); TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; COGs: COG4359 conserved hypothetical protein; InterPro IPR005834:IPR006383; KEGG: cyc:PCC7424_0306 HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase-like hydrolase; SPTR:2-hydroxy-3-keto-5-methylthiopentenyl-1-phosph atephosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IB, PSPase-like.
  
  
 0.524
cbbL
Ribulose 1,5-bisphosphate carboxylase large subunit; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.
  
  
 0.449
AFZ05524.1
PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484; KEGG: cyc:PCC7424_5151 carbohydrate kinase FGGY; PFAM: Carbohydrate kinase, FGGY, N-terminal; SPTR: Carbohydrate kinase, FGGY.
  
  
 0.445
AFZ09625.1
PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR015590:IPR001670; KEGG: cyc:PCC7424_3674 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type; Aldehyde dehydrogenase domain; PRIAM: Acetaldehyde dehydrogenase (acetylating); SPTR: Alcohol dehydrogenase, iron-containing family; alcohol dehydrogenase AdhE; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.445
mtnD
Acireductone dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
  
  
 0.412
AFZ09245.1
Acireductone dioxygenase apoprotein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
  
  
 0.412
AFZ08343.1
PFAM: HI0933-like protein; TIGRFAM: flavoprotein, HI0933 family; COGs: COG2081 flavoprotein; InterPro IPR004792; KEGG: cyc:PCC7424_3520 HI0933 family protein; PFAM: Conserved hypothetical protein CHP00275, flavoprotein HI0933-like; SPTR: Fumarate reductase/succinate dehydrogenase flavoprotein-like protein; TIGRFAM: Conserved hypothetical protein CHP00275, flavoprotein HI0933-like.
       0.404
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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