STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ08871.1Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: npu:Npun_F5193 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Hi [...] (590 aa)    
Predicted Functional Partners:
AFZ05272.1
Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: cyc:PCC7424_1341 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response re [...]
 
 0.979
AFZ05081.1
Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: ava:Ava_1447 two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR [...]
  0.971
AFZ05704.1
Multi-component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; Hpt domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867:IPR008207; KEGG: ava:Ava_1629 multi-component transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; SMART: Signal transduction [...]
 
 
 0.899
AFZ05181.1
Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: ter:Tery_4323 two component LuxR family transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SPTR: Two component LuxR family tra [...]
 
 
   0.834
AFZ04715.1
Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: ter:Tery_4937 two component transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPT [...]
 
   0.817
AFZ08570.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: npu:Npun_F5961 response regulator receiver, CheY; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver protein.
 
   0.811
AFZ09709.1
Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: ana:all1736 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SPTR: Two component LuxR family transcriptional regulator.
 
 
   0.803
AFZ08235.1
Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: cyb:CYB_1044 LuxR family DNA-binding response regulator; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SPTR: Response regulator receiver [...]
 
   0.801
AFZ05774.1
PFAM: Response regulator receiver domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: cyb:CYB_1937 response regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator.
  
   0.799
AFZ08706.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR001610:IPR003661:IPR 003594:IPR008207:IPR013655:IPR013767; KEGG: syp:SYNPCC7002_A1261 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; Signal transduction response regulator, receiver domain [...]
 
 
0.799
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.