STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AFZ08951.1Serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: serine O-acetyltransferase; COGs: COG1045 Serine acetyltransferase; InterPro IPR001451:IPR005881; KEGG: ava:Ava_1668 serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPTR: Serine O-acetyltransferase; TIGRFAM: Serine O-acetyltransferase. (263 aa)    
Predicted Functional Partners:
AFZ07431.1
Cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: naz:Aazo_3782 cysteine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.979
AFZ08947.1
Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: npu:Npun_R0343 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase A; Cysteine synthase K/M; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.979
AFZ07046.1
Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001926; KEGG: cyj:Cyan7822_5337 pyridoxal-5'-phosphate-dependent protein subunit beta; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase.
 
 0.961
cysS
PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803:IPR015273; KEGG: cyc:PCC7424_2722 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia; Cysteinyl-tRNA synthetase, class Ia, DALR; PRIAM: Cysteine--tRNA ligase; SMART: Cysteinyl-tRNA synthetase, class Ia, DALR; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.936
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.822
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
     
 0.821
AFZ10059.1
PFAM: Homoserine dehydrogenase, NAD binding domain; Homoserine dehydrogenase; ACT domain; COGs: COG0460 Homoserine dehydrogenase; InterPro IPR005106:IPR001342:IPR002912; KEGG: ter:Tery_4567 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase.
     
 0.811
trpB
Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.806
trpA
Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.806
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
     
 0.802
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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