STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AFZ09058.1PFAM: Polynucleotide kinase 3 phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase family domain; COGs: COG0241 Histidinol phosphatase and related phosphatase; InterPro IPR006543:IPR006549; KEGG: cyc:PCC7424_2660 histidinol-phosphate phosphatase family protein; SPTR: D,D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: Histidinol-phosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA. (193 aa)    
Predicted Functional Partners:
AFZ08462.1
rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
 
  
 0.981
AFZ08849.1
rfaE bifunctional protein; PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I; COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR011611:IPR011913; KEGG: cyc:PCC7424_0338 RfaE bifunctional protein; PFAM: Carbohydrate/purine kinase; SPTR: ADP-heptose synthase; TIGRFAM: RfaE bifunctional protein, domain I.
 
  
 0.981
hisI
PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; HAMAP: Phosphoribosyl-ATP pyrophosphohydrolase; Histidine biosynthesis bifunctional protein HisIE; InterPro IPR008179:IPR023019:IPR002496:IPR021130; KEGG: naz:Aazo_2676 phosphoribosyl-ATP diphosphatase; PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; PRIAM: Phosphoribosyl-AMP cyclohydrolase., Phosphoribosyl-ATP diphosphatase; SPTR: Bifunctional phosphoribosyl-AMP cycloh [...]
  
  
 0.970
cugP
Mannose-1-phosphate guanylyltransferase; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate.
 
 
 0.922
AFZ08662.1
Hypothetical protein; PFAM: ATP dependent DNA ligase domain; COGs: COG1793 ATP-dependent DNA ligase; KEGG: nar:Saro_1695 ATP dependent DNA ligase; SPTR: Putative uncharacterized protein.
   
 0.780
hisH
Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.762
AFZ09042.1
PFAM: Glycosyltransferase family 9 (heptosyltransferase); COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: ter:Tery_0610 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 9; SPTR: Glycosyl transferase family protein.
 
   
 0.740
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.698
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
  
 0.696
hisA
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; HAMAP: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; InterPro IPR006062:IPR006063:IPR023016; KEGG: cyc:PCC7424_4950 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthe [...]
  
  
 0.695
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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