STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ09060.1PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3920 Signal transduction histidine kinase; InterProIPR013656:IPR013767:IPR013655:IPR011495:IPR 003594:IPR000014:IPR001610; KEGG: cyn:Cyan7425_2336 signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain; PAS fold-3; PAS fold-4; PAS fold; ATPase-like, ATP-binding domain; SMART: PAS; PAC motif; ATPase-like, ATP-binding domain; SPTR: Signal transduction histidine kinase; TIGRFAM: PAS. (975 aa)    
Predicted Functional Partners:
AFZ09059.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR001789:IPR003661:IPR003594; KEGG: cyj:Cyan7822_3901 response regulator receiver sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: Signal transduction response regulator, receiver domain; Signal transductio [...]
 
 0.914
AFZ09704.1
GAF sensor hybrid histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003018:IPR003661:IPR003594:IPR 001789; KEGG: ava:Ava_4696 GAF sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-bindin [...]
  
 
 0.839
AFZ07816.1
Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR003661:IPR003594:IPR 001054; KEGG: ter:Tery_3155 adenylate/guanylate cyclase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor dom [...]
  
 
 0.824
AFZ08740.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR001610:IPR003018:IPR 003661:IPR003594:IPR013655:IPR013767; KEGG: npu:Npun_R3691 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; PAS fold-3; GAF; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor do [...]
 
 
0.709
AFZ08604.1
Multi-sensor hybrid histidine kinase; PFAM: CBS domain; Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; Hpt domain; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR000644:IPR001610:IPR003018:IPR 003661:IPR003594:IPR001789:IPR013655:IPR013767:IPR008207; KEGG: ter:Tery_4447 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domai [...]
 
 0.692
AFZ08766.1
PFAM: GAF domain; GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR003018:IPR001789; KEGG: cyj:Cyan7822_2479 response regulator receiver modulated diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; GAF; Signal transduction response regulator, receiver domain; SMART: Diguanylate cyclase, predicted; GAF; SPTR: Putative GGDEF domain protein; TIGRFAM: Diguanylate cyclase, predicted.
 
 0.683
AFZ08761.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR001789:IPR003661:IPR003594; KEGG: cyh:Cyan8802_1302 multi-sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dim [...]
 
 0.645
AFZ07356.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR001610:IPR003661:IPR 003594:IPR013655:IPR013656; KEGG: npu:Npun_R4211 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; Signal transduction response regulator, receiver domain; PAS fold-4; SMART: ATPase-lik [...]
 
 
0.623
AFZ08196.1
PFAM: EAL domain; Response regulator receiver domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterPro IPR001789:IPR000160:IPR001633; KEGG: cyj:Cyan7822_4052 response regulator receiver modulated diguanylate cyclase/phosphodiesterase; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver domain; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; Signal transduction response regulator, receiver domain; SPTR: Putative Cyclic diguanyl [...]
 
 
 0.622
AFZ05847.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; GAF domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003660:IPR003018:IPR013655:IPR 013656:IPR003661:IPR003594:IPR001789:IPR008207:IPR001610; KEGG: npu:Npun_F2363 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; GAF; HAMP linker domain; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domai [...]
 
 
0.621
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.