STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ09570.1PFAM: tRNA (Uracil-5-)-methyltransferase; TRAM domain; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR001566:IPR002792:IPR003402; KEGG: ana:alr3654 hypothetical protein; PFAM: Deoxyribonuclease/rho motif-related TRAM; Protein of unknown function Met10; SPTR: 23S rRNA (Uracil-5-)-methyltransferase RumA; TIGRFAM: 23S rRNA methyltransferase/RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (470 aa)    
Predicted Functional Partners:
rsmI
Protein of unknown function UPF0011; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
  
 0.591
AFZ05401.1
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
 
  
 0.559
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.555
AFZ05147.1
tRNA/rRNA methyltransferase (SpoU); PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; COGs: COG0566 rRNA methylase; InterPro IPR013123:IPR001537; KEGG: npu:Npun_F5720 tRNA/rRNA methyltransferase (SpoU); PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; SMART: RNA 2-O ribose methyltransferase, substrate binding; SPTR: TRNA/rRNA methyltransferase (SpoU); Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
  
 0.550
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
 
  
 0.548
prmA
Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
 
   
 0.545
AFZ07343.1
RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; COGs: COG0566 rRNA methylase; InterPro IPR004441:IPR013123:IPR001537; KEGG: mar:MAE_28400 tRNA/rRNA methyltransferase; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; SMART: RNA 2-O ribose methyltransferase, substrate binding; SPTR: tRNA/rRNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; Belongs to the class IV-like SAM-binding methyltransferase sup [...]
 
  
 0.518
AFZ08657.1
Fmu (Sun) domain protein; PFAM: NOL1/NOP2/sun family; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: ana:alr1008 hypothetical protein; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; SPTR: Fmu (Sun)/nucleolar NOL1/Nop2p; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.496
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
  
 0.480
rsmG
16S rRNA m(7)G-527 methyltransferase; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
    0.477
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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