node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFZ09140.1 | AFZ09722.1 | Osc7112_4872 | Osc7112_5495 | PFAM: NUDIX domain; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: npu:Npun_R5813 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: Mutator protein. | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.493 |
AFZ09721.1 | AFZ09722.1 | Osc7112_5494 | Osc7112_5495 | 1,4-dihydroxy-2-naphthoyl-CoA hydrolase; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis; Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily. | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.448 |
AFZ09722.1 | AFZ09140.1 | Osc7112_5495 | Osc7112_4872 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | PFAM: NUDIX domain; COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR000086; KEGG: npu:Npun_R5813 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: Mutator protein. | 0.493 |
AFZ09722.1 | AFZ09721.1 | Osc7112_5495 | Osc7112_5494 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 1,4-dihydroxy-2-naphthoyl-CoA hydrolase; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis; Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily. | 0.448 |
AFZ09722.1 | AFZ09945.1 | Osc7112_5495 | Osc7112_5734 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 2OG-Fe(II) oxygenase; COGs: COG3145 Alkylated DNA repair protein; KEGG: cyn:Cyan7425_0803 2OG-Fe(II) oxygenase; SPTR: Oxidoreductase, 2OG-Fe(II) oxygenase family. | 0.682 |
AFZ09722.1 | panB | Osc7112_5495 | Osc7112_5797 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.935 |
AFZ09722.1 | panC/cmk | Osc7112_5495 | Osc7112_2235 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. | 0.938 |
AFZ09722.1 | ribBA | Osc7112_5495 | Osc7112_5668 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.400 |
AFZ09945.1 | AFZ09722.1 | Osc7112_5734 | Osc7112_5495 | 2OG-Fe(II) oxygenase; COGs: COG3145 Alkylated DNA repair protein; KEGG: cyn:Cyan7425_0803 2OG-Fe(II) oxygenase; SPTR: Oxidoreductase, 2OG-Fe(II) oxygenase family. | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.682 |
panB | AFZ09722.1 | Osc7112_5797 | Osc7112_5495 | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.935 |
panB | panC/cmk | Osc7112_5797 | Osc7112_2235 | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. | 0.998 |
panB | ribBA | Osc7112_5797 | Osc7112_5668 | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.427 |
panC/cmk | AFZ09722.1 | Osc7112_2235 | Osc7112_5495 | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.938 |
panC/cmk | panB | Osc7112_2235 | Osc7112_5797 | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.998 |
panC/cmk | ribBA | Osc7112_2235 | Osc7112_5668 | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.486 |
ribBA | AFZ09722.1 | Osc7112_5668 | Osc7112_5495 | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.400 |
ribBA | panB | Osc7112_5668 | Osc7112_5797 | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.427 |
ribBA | panC/cmk | Osc7112_5668 | Osc7112_2235 | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. | 0.486 |