node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFZ05209.1 | AFZ05668.1 | Osc7112_0616 | Osc7112_1118 | TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR014008; KEGG: ava:Ava_1817 precorrin-6B methylase; SPTR: Precorrin-6B methylase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core. | Precorrin-8X methylmutase CbiC/CobH; PFAM: MerR, DNA binding; MerR family regulatory protein; Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR000551:IPR003722; KEGG: ana:alr3162 transcriptional regulator; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator. | 0.761 |
AFZ05209.1 | AFZ06793.1 | Osc7112_0616 | Osc7112_2345 | TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR014008; KEGG: ava:Ava_1817 precorrin-6B methylase; SPTR: Precorrin-6B methylase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core. | PFAM: Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: ava:Ava_2866 precorrin-8X methylmutase; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase. | 0.937 |
AFZ05209.1 | AFZ08482.1 | Osc7112_0616 | Osc7112_4157 | TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR014008; KEGG: ava:Ava_1817 precorrin-6B methylase; SPTR: Precorrin-6B methylase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core. | Precorrin-3 methyltransferase; PFAM: Cobalamin biosynthesis central region; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; TIGRFAM: precorrin-3B C17-methyltransferase; COGs: COG1010 Precorrin-3B methylase; InterPro IPR002750:IPR000878:IPR006363; KEGG: ana:all0453 cobalamin biosynthesis precorrin-3 methylase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CbiG, core; PRIAM: Precorrin-3B C(17)-methyltransferase; SPTR: Precorrin-3 methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferas [...] | 0.962 |
AFZ05209.1 | AFZ08836.1 | Osc7112_0616 | Osc7112_4541 | TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR014008; KEGG: ava:Ava_1817 precorrin-6B methylase; SPTR: Precorrin-6B methylase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core. | Precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase; COGs: COG2875 Precorrin-4 methylase; InterPro IPR006362:IPR000878; KEGG: ana:all4698 precorrin-3 methylase; PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: Precorrin-4 C11-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core. | 0.933 |
AFZ05209.1 | AFZ09594.1 | Osc7112_0616 | Osc7112_5356 | TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR014008; KEGG: ava:Ava_1817 precorrin-6B methylase; SPTR: Precorrin-6B methylase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core. | PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR012818:IPR014008:IPR000878; KEGG: ter:Tery_0210 precorrin-6Y C5,15-methyltransferase (decarboxylating); PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: Precorrin-6Y C5,15-methyltransferase (Decarboxylating); TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransfera [...] | 0.656 |
AFZ05209.1 | AFZ09813.1 | Osc7112_0616 | Osc7112_5590 | TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR014008; KEGG: ava:Ava_1817 precorrin-6B methylase; SPTR: Precorrin-6B methylase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core. | PFAM: Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: ter:Tery_3745 precorrin-8X methylmutase; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; SPTR: Precorrin-8X methylmutase. | 0.938 |
AFZ05209.1 | cbiA | Osc7112_0616 | Osc7112_2821 | TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR014008; KEGG: ava:Ava_1817 precorrin-6B methylase; SPTR: Precorrin-6B methylase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.888 |
AFZ05209.1 | cbiD | Osc7112_0616 | Osc7112_4276 | TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR014008; KEGG: ava:Ava_1817 precorrin-6B methylase; SPTR: Precorrin-6B methylase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core. | cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.888 |
AFZ05209.1 | cobQ | Osc7112_0616 | Osc7112_4990 | TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR014008; KEGG: ava:Ava_1817 precorrin-6B methylase; SPTR: Precorrin-6B methylase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.792 |
AFZ05668.1 | AFZ05209.1 | Osc7112_1118 | Osc7112_0616 | Precorrin-8X methylmutase CbiC/CobH; PFAM: MerR, DNA binding; MerR family regulatory protein; Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR000551:IPR003722; KEGG: ana:alr3162 transcriptional regulator; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator. | TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR014008; KEGG: ava:Ava_1817 precorrin-6B methylase; SPTR: Precorrin-6B methylase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core. | 0.761 |
AFZ05668.1 | AFZ06793.1 | Osc7112_1118 | Osc7112_2345 | Precorrin-8X methylmutase CbiC/CobH; PFAM: MerR, DNA binding; MerR family regulatory protein; Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR000551:IPR003722; KEGG: ana:alr3162 transcriptional regulator; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator. | PFAM: Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: ava:Ava_2866 precorrin-8X methylmutase; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase. | 0.913 |
AFZ05668.1 | AFZ08482.1 | Osc7112_1118 | Osc7112_4157 | Precorrin-8X methylmutase CbiC/CobH; PFAM: MerR, DNA binding; MerR family regulatory protein; Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR000551:IPR003722; KEGG: ana:alr3162 transcriptional regulator; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator. | Precorrin-3 methyltransferase; PFAM: Cobalamin biosynthesis central region; Tetrapyrrole (Corrin/Porphyrin) Methylases; Cobalamin synthesis G N-terminal; TIGRFAM: precorrin-3B C17-methyltransferase; COGs: COG1010 Precorrin-3B methylase; InterPro IPR002750:IPR000878:IPR006363; KEGG: ana:all0453 cobalamin biosynthesis precorrin-3 methylase; PFAM: Tetrapyrrole methylase; Cobalamin (vitamin B12) biosynthesis CbiG, core; PRIAM: Precorrin-3B C(17)-methyltransferase; SPTR: Precorrin-3 methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferas [...] | 0.983 |
AFZ05668.1 | AFZ08836.1 | Osc7112_1118 | Osc7112_4541 | Precorrin-8X methylmutase CbiC/CobH; PFAM: MerR, DNA binding; MerR family regulatory protein; Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR000551:IPR003722; KEGG: ana:alr3162 transcriptional regulator; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator. | Precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase; COGs: COG2875 Precorrin-4 methylase; InterPro IPR006362:IPR000878; KEGG: ana:all4698 precorrin-3 methylase; PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: Precorrin-4 C11-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core. | 0.841 |
AFZ05668.1 | AFZ09001.1 | Osc7112_1118 | Osc7112_4714 | Precorrin-8X methylmutase CbiC/CobH; PFAM: MerR, DNA binding; MerR family regulatory protein; Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR000551:IPR003722; KEGG: ana:alr3162 transcriptional regulator; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator. | PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR000878:IPR012818:IPR014008; KEGG: mar:MAE_02680 precorrin-6y C5,15-methyltransferase (decarboxylating); PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: Precorrin-6Y C(5,15)-methyltransferase (Decarboxylating); TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransfe [...] | 0.996 |
AFZ05668.1 | AFZ09594.1 | Osc7112_1118 | Osc7112_5356 | Precorrin-8X methylmutase CbiC/CobH; PFAM: MerR, DNA binding; MerR family regulatory protein; Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR000551:IPR003722; KEGG: ana:alr3162 transcriptional regulator; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator. | PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR012818:IPR014008:IPR000878; KEGG: ter:Tery_0210 precorrin-6Y C5,15-methyltransferase (decarboxylating); PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: Precorrin-6Y C5,15-methyltransferase (Decarboxylating); TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransfera [...] | 0.997 |
AFZ05668.1 | AFZ09813.1 | Osc7112_1118 | Osc7112_5590 | Precorrin-8X methylmutase CbiC/CobH; PFAM: MerR, DNA binding; MerR family regulatory protein; Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR000551:IPR003722; KEGG: ana:alr3162 transcriptional regulator; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator. | PFAM: Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: ter:Tery_3745 precorrin-8X methylmutase; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; SPTR: Precorrin-8X methylmutase. | 0.924 |
AFZ05668.1 | cbiA | Osc7112_1118 | Osc7112_2821 | Precorrin-8X methylmutase CbiC/CobH; PFAM: MerR, DNA binding; MerR family regulatory protein; Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR000551:IPR003722; KEGG: ana:alr3162 transcriptional regulator; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.969 |
AFZ05668.1 | cbiD | Osc7112_1118 | Osc7112_4276 | Precorrin-8X methylmutase CbiC/CobH; PFAM: MerR, DNA binding; MerR family regulatory protein; Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR000551:IPR003722; KEGG: ana:alr3162 transcriptional regulator; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator. | cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.812 |
AFZ05668.1 | cobQ | Osc7112_1118 | Osc7112_4990 | Precorrin-8X methylmutase CbiC/CobH; PFAM: MerR, DNA binding; MerR family regulatory protein; Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR000551:IPR003722; KEGG: ana:alr3162 transcriptional regulator; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; HTH transcriptional regulator, MerR; SMART: HTH transcriptional regulator, MerR; SPTR: Transcriptional regulator. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.783 |
AFZ06793.1 | AFZ05209.1 | Osc7112_2345 | Osc7112_0616 | PFAM: Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: ava:Ava_2866 precorrin-8X methylmutase; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase. | TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR014008; KEGG: ava:Ava_1817 precorrin-6B methylase; SPTR: Precorrin-6B methylase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core. | 0.937 |