STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sigARNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (388 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 0.890
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.872
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.843
secA
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
 
 
 0.753
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.744
rpoC1
DNA-directed RNA polymerase gamma chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.743
rpoC2
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
 
 
 0.743
AFZ06006.1
DNA-O6-methylguanine--protein-cysteine S-methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase; COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048:IPR000005:IPR018060; KEGG: cyp:PCC8801_2345 transcriptional regulator, AraC family; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; HTH transcriptional regulator, AraC; SMART: Helix-turn-helix, AraC type, DNA binding domain; SPTR: Transcriptional regulator, AraC family; TIGRFAM: Methylated-DNA-[protein]- [...]
   
 
 0.738
AFZ09460.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; CBS domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterProIPR000014:IPR000160:IPR000644:IPR001610:IPR 001633:IPR013767; KEGG: npu:Npun_F5467 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS fold; Cystathionine beta-synthase, core; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAC motif; PA [...]
   
 
 0.681
nusA
NusA antitermination factor; Participates in both transcription termination and antitermination.
 
 
 0.632
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.