STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ureCPFAM: Urease alpha-subunit, N-terminal domain; Amidohydrolase family; TIGRFAM: urease, alpha subunit; COGs: COG0804 Urea amidohydrolase (urease) alpha subunit; HAMAP: Urease, alpha subunit; InterPro IPR005848:IPR011612:IPR006680; KEGG: ava:Ava_3618 urease subunit alpha; PFAM: Amidohydrolase 1; Urease alpha-subunit, N-terminal; PRIAM: Urease; SPTR: Urease subunit alpha; TIGRFAM: Urease, alpha subunit. (607 aa)    
Predicted Functional Partners:
ureA
PFAM: Urease, gamma subunit; TIGRFAM: urease, gamma subunit; COGs: COG0831 Urea amidohydrolase (urease) gamma subunit; HAMAP: Urease, gamma subunit; InterPro IPR012010:IPR002026; KEGG: npu:Npun_F0823 urease subunit gamma; PFAM: Urease, alpha/gamma subunit; PRIAM: Urease; SPTR: Urease subunit gamma; TIGRFAM: Urease, alpha/gamma subunit; Belongs to the urease gamma subunit family.
 0.999
ureB
PFAM: Urease beta subunit; TIGRFAM: urease, beta subunit; COGs: COG0832 Urea amidohydrolase (urease) beta subunit; HAMAP: Urease, beta subunit; InterPro IPR002019; KEGG: npu:Npun_F0824 urease subunit beta; PFAM: Urease, beta subunit; PRIAM: Urease; SPTR: Urease subunit beta; TIGRFAM: Urease, beta subunit; Belongs to the urease beta subunit family.
 0.999
ureF
Urease accessory protein ureF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.994
ureG
Urease accessory protein ureG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
 0.992
ureE
Urease accessory protein ureE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.985
ureD
Urease accessory protein ureD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
  
 0.956
AFZ06131.1
Urea carboxylase; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; Carbamoyl-phosphate synthase L chain, N-terminal domain; Biotin-requiring enzyme; TIGRFAM: urea carboxylase; biotin-dependent carboxylase uncharacterized domain; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterProIPR014084:IPR003778:IPR005481:IPR005479:IPR 005482:IPR003833:IPR000089; KEGG: cyn:Cyan7425_2304 UreA carboxylase; PFAM: Allophanate hydrolase subunit 2; Carbamoyl-phosphate s [...]
    
 0.936
AFZ06104.1
PFAM: Amidase; TIGRFAM: allophanate hydrolase; COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR014085:IPR000120; KEGG: gvi:glr0961 allophanate hydrolase; PFAM: Amidase; PRIAM: Allophanate hydrolase; SPTR: Glr0961 protein; TIGRFAM: Allophanate hydrolase.
     
  0.900
AFZ05968.1
PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392:IPR003495; KEGG: syp:SYNPCC7002_A0203 hydrogenase isoenzymes formation protein; HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB.
  
  
 0.696
AFZ10164.1
Hypothetical protein; COGs: COG4421 Capsular polysaccharide biosynthesis protein; KEGG: sli:Slin_6880 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.456
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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