STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (211 aa)    
Predicted Functional Partners:
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.951
pyrE
Orotidine-5'-phosphate decarboxylase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 0.945
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.921
AFZ07228.1
Cytosine deaminase; PFAM: Amidohydrolase family; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR013108; KEGG: rxy:Rxyl_0224 N-isopropylammelide isopropylaminohydrolase; PFAM: Amidohydrolase 3; PRIAM: Cytosine deaminase; SPTR: Amidohydrolase family, putative.
  
 
 0.920
AFZ10205.1
PFAM: Amidohydrolase family; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR013108; KEGG: ter:Tery_4570 cytosine deaminase-like protein; PFAM: Amidohydrolase 3; SPTR: Amidohydrolase 3.
  
 
 0.920
pyrR
Bifunctional protein pyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.919
AFZ09457.1
PFAM: Phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase; COGs: COG0035 Uracil phosphoribosyltransferase; InterPro IPR005765:IPR000836; KEGG: ana:all2063 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; TIGRFAM: Uracil phosphoribosyl transferase; Belongs to the UPRTase family.
  
  
 
0.910
surE
5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.905
AFZ10273.1
5'-nucleotidase; PFAM: Survival protein SurE; TIGRFAM: 5'/3'-nucleotidase SurE; COGs: COG0496 acid phosphatase; InterPro IPR002828; KEGG: cyt:cce_2598 stationary phase survival protein SurE; PFAM: Survival protein SurE-like phosphatase/nucleotidase; SPTR: Putative 5'-nucleotidase; TIGRFAM: Survival protein SurE-like phosphatase/nucleotidase; exopolyphosphatase.
     
 0.905
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.893
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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