STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFZ10249.1ATP-dependent DNA helicase RecQ; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterProIPR014001:IPR001650:IPR018982:IPR002121:IPR 006293:IPR004589:IPR011545; KEGG: ter:Tery_3264 ATP-dependent DNA helicase RecQ; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; SMART: RQC domain; DEAD-like helicase, N-terminal; Helicase, C-terminal; He [...] (731 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
 0.962
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.946
AFZ08133.1
PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR014001:IPR001650:IPR011545; KEGG: ter:Tery_3732 DEAD/DEAH box helicase-like; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: DEAD/DEAH box helicase-like; Belongs to the DEAD box helicase family.
 
0.933
AFZ07536.1
ATP-dependent DNA helicase RecQ; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterPro IPR004589:IPR014001:IPR001650:IPR011545; KEGG: ana:alr4842 ATP-dependent DNA helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: ATP-dependent DNA helicase RecQ; TIGRFAM: DNA helicase, ATP-dependent, RecQ type.
  
  
 
0.918
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.827
AFZ05703.1
PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain; InterPro IPR000330:IPR001650:IPR014001; KEGG: npu:Npun_F6355 helicase domain-containing protein; PFAM: Helicase, C-terminal; SNF2-related; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: Helicase domain protein.
  
 
 0.823
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
 0.788
AFZ04966.1
PFAM: Glycosyl transferases group 1; Glycosyl transferase family 2; COGs: COG0438 Glycosyltransferase; InterPro IPR001173:IPR001296; KEGG: ter:Tery_1360 glycosyl transferase, group 1; PFAM: Glycosyl transferase, group 1; Glycosyl transferase, family 2; SPTR: Glycosyl transferase, group 1.
  
 
 0.756
AFZ05529.1
PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212:IPR005751; KEGG: ava:Ava_3361 ATP-dependent DNA helicase Rep; PFAM: DNA helicase, UvrD/REP type; SPTR: ATP-dependent DNA helicase PcrA; TIGRFAM: DNA helicase, ATP-dependent, PcrA type.
 
 
 0.732
AFZ06448.1
KEGG: npu:Npun_R4248 hypothetical protein; SPTR: Putative uncharacterized protein.
  
 
 0.732
Your Current Organism:
Oscillatoria nigroviridis
NCBI taxonomy Id: 179408
Other names: O. nigro-viridis PCC 7112, Oscillatoria nigro-viridis PCC 7112, Oscillatoria sp. PCC 7112
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