STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDQ45643.1acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa)    
Predicted Functional Partners:
CDQ44809.1
3-ketoacyl-CoA thiolase.
  
 0.996
CDQ45296.1
3-hydroxyacyl-CoA dehydrogenase.
 
 0.996
fadB2
3-hydroxybutyryl-CoA dehydrogenase.
 0.985
CDQ43219.1
acyl-CoA dehydrogenase domain-containing protein.
  
 0.943
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 
 0.928
CDQ45974.1
3-hydroxy-3-methylglutaryl-CoA lyase.
  
 
 0.924
leuA-2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.924
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.917
CDQ46815.1
Methylmalonate-semialdehyde dehydrogenase.
  
 0.911
CDQ47064.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
     
 0.905
Your Current Organism:
Mycolicibacterium neoaurum
NCBI taxonomy Id: 1795
Other names: ATCC 25795, CCUG 37665, CIP 105387, DSM 44074, HAMBI 2273, JCM 6365, M. neoaurum, Mycobacterium neoaurum, Mycobacterium sp. ATCC 23071, Mycobacterium sp. ATCC 25798, Mycobacterium sp. ATCC 25799, Mycobacterium sp. ATCC 25800, Mycobacterium sp. ATCC 25803, Mycobacterium sp. ATCC 27277, NCTC 10818
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