STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfuAHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.944
feoB
Iron transporter FeoB; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
 
   
 0.915
KLO48437.1
Iron-sulfur cluster insertion protein ErpA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family.
  
 
 0.782
nuoI
NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.781
nifU
Nitrogen fixation protein NifU; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.749
sdhB
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.741
frdB
Catalyzes the fumarate and succinate interconversion; fumarate reductase is used under anaerobic conditions with glucose or glycerol as carbon source; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.741
KLO52648.1
Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.707
KLO48664.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.541
KLO50467.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.513
Your Current Organism:
Mycolicibacterium senegalense
NCBI taxonomy Id: 1796
Other names: ATCC 35796, CCUG 21001, CIP 104941, DSM 43656, JCM 15467, Mycobacterium farcinogenes subsp. senegalense, Mycobacterium senegalense, NCTC 10956, strain IEMVT 378
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