node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KLO54553.1 | lexA | ABW05_04490 | ABW05_04495 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ArsR family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.593 |
KLO54553.1 | nrdR | ABW05_04490 | ABW05_04485 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.649 |
btuR | cobK | ABW05_05010 | ABW05_26630 | Cobinamide adenolsyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | cobalt-precorrin-6X reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.922 |
btuR | cobL | ABW05_05010 | ABW05_26640 | Cobinamide adenolsyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.939 |
btuR | cobN | ABW05_05010 | ABW05_26595 | Cobinamide adenolsyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CobN; With CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
btuR | nrdR | ABW05_05010 | ABW05_04485 | Cobinamide adenolsyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.700 |
cobK | btuR | ABW05_26630 | ABW05_05010 | cobalt-precorrin-6X reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobinamide adenolsyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.922 |
cobK | cobL | ABW05_26630 | ABW05_26640 | cobalt-precorrin-6X reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
cobK | cobN | ABW05_26630 | ABW05_26595 | cobalt-precorrin-6X reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CobN; With CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.957 |
cobK | nrdR | ABW05_26630 | ABW05_04485 | cobalt-precorrin-6X reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.717 |
cobK | recD | ABW05_26630 | ABW05_10650 | cobalt-precorrin-6X reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exodeoxyribonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] | 0.481 |
cobL | btuR | ABW05_26640 | ABW05_05010 | precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobinamide adenolsyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.939 |
cobL | cobK | ABW05_26640 | ABW05_26630 | precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | cobalt-precorrin-6X reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
cobL | cobN | ABW05_26640 | ABW05_26595 | precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CobN; With CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.986 |
cobL | nrdR | ABW05_26640 | ABW05_04485 | precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NrdR family transcriptional regulator; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.707 |
cobL | recD | ABW05_26640 | ABW05_10650 | precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exodeoxyribonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and re [...] | 0.481 |
cobL | ribD_1 | ABW05_26640 | ABW05_03150 | precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.684 |
cobN | btuR | ABW05_26595 | ABW05_05010 | Cobalamin biosynthesis protein CobN; With CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobinamide adenolsyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.994 |
cobN | cobK | ABW05_26595 | ABW05_26630 | Cobalamin biosynthesis protein CobN; With CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | cobalt-precorrin-6X reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.957 |
cobN | cobL | ABW05_26595 | ABW05_26640 | Cobalamin biosynthesis protein CobN; With CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology. | precorrin-6Y-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.986 |