| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KLO54585.1 | serA_1 | ABW05_05835 | ABW05_05845 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.644 |
| KLO54585.1 | yyaP_2 | ABW05_05835 | ABW05_05830 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.634 |
| fgs | gcvP | ABW05_28885 | ABW05_00555 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.487 |
| fgs | gcvT | ABW05_28885 | ABW05_27640 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.614 |
| fgs | metH_1 | ABW05_28885 | ABW05_26960 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.703 |
| fgs | ribD_1 | ABW05_28885 | ABW05_03150 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.804 |
| fgs | serA_1 | ABW05_28885 | ABW05_05845 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.589 |
| fgs | thyA | ABW05_28885 | ABW05_04755 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.974 |
| fgs | yyaP_1 | ABW05_28885 | ABW05_23160 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.658 |
| fgs | yyaP_2 | ABW05_28885 | ABW05_05830 | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.658 |
| gcvH | gcvP | ABW05_00530 | ABW05_00555 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
| gcvH | gcvT | ABW05_00530 | ABW05_27640 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| gcvH | metH_1 | ABW05_00530 | ABW05_26960 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.928 |
| gcvH | serA_1 | ABW05_00530 | ABW05_05845 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.513 |
| gcvH | thyA | ABW05_00530 | ABW05_04755 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.904 |
| gcvH | yyaP_1 | ABW05_00530 | ABW05_23160 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.660 |
| gcvH | yyaP_2 | ABW05_00530 | ABW05_05830 | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.660 |
| gcvP | fgs | ABW05_00555 | ABW05_28885 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.487 |
| gcvP | gcvH | ABW05_00555 | ABW05_00530 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| gcvP | gcvT | ABW05_00555 | ABW05_27640 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |