Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
phoUPhoU family transcriptional regulator; Plays a role in the regulation of phosphate uptake. (219 aa)    
Predicted Functional Partners:
pstB
Phosphate ABC transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
 
 
 0.978
pstA
Phosphate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.977
pstC2
Phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
  
 0.862
pstS3
Phosphate-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family.
 
 
 0.826
yaeQ
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.686
choD
Cholesterol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.590
senX3
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.579
guaB_2
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.467
gltB_2
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.464
gltB_3
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.464
Your Current Organism:
Mycolicibacterium senegalense
NCBI taxonomy Id: 1796
Other names: ATCC 35796, CCUG 21001, CIP 104941, DSM 43656, JCM 15467, Mycobacterium farcinogenes subsp. senegalense, Mycobacterium senegalense, NCTC 10956, strain IEMVT 378
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