node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KLO51684.1 | guaA_1 | ABW05_09265 | ABW05_27330 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.859 |
KLO51684.1 | guaA_2 | ABW05_09265 | ABW05_09200 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.995 |
KLO51684.1 | guaB_1 | ABW05_09265 | ABW05_00595 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.946 |
KLO51684.1 | guaB_2 | ABW05_09265 | ABW05_09270 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.980 |
KLO51684.1 | hpt | ABW05_09265 | ABW05_19140 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.888 |
KLO51684.1 | pheT | ABW05_09265 | ABW05_26155 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | phenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.810 |
KLO51684.1 | purA | ABW05_09265 | ABW05_12875 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.970 |
KLO51684.1 | purH | ABW05_09265 | ABW05_21995 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.928 |
KLO51684.1 | rdgB | ABW05_09265 | ABW05_30360 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.905 |
KLO51684.1 | rpoZ | ABW05_09265 | ABW05_03245 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.737 |
guaA_1 | KLO51684.1 | ABW05_27330 | ABW05_09265 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.859 |
guaA_1 | guaA_2 | ABW05_27330 | ABW05_09200 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.751 |
guaA_1 | guaB_1 | ABW05_27330 | ABW05_00595 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.828 |
guaA_1 | guaB_2 | ABW05_27330 | ABW05_09270 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.899 |
guaA_1 | hpt | ABW05_27330 | ABW05_19140 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.776 |
guaA_1 | pheT | ABW05_27330 | ABW05_26155 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | phenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.719 |
guaA_1 | purA | ABW05_27330 | ABW05_12875 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.414 |
guaA_1 | purH | ABW05_27330 | ABW05_21995 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.440 |
guaA_1 | rdgB | ABW05_27330 | ABW05_30360 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-triphosphate diphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.748 |
guaA_2 | KLO51684.1 | ABW05_09200 | ABW05_09265 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.995 |