STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ald_3Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. (366 aa)    
Predicted Functional Partners:
pntB
Pyridine nucleotide transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
   
  0.952
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
 
 0.928
aspC_2
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.675
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
  0.670
pntA
NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 
0.591
aspC_1
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.590
ppnK
Inorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.561
cfiB
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
       0.500
KLO54816.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.440
nadR
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.435
Your Current Organism:
Mycolicibacterium senegalense
NCBI taxonomy Id: 1796
Other names: ATCC 35796, CCUG 21001, CIP 104941, DSM 43656, JCM 15467, Mycobacterium farcinogenes subsp. senegalense, Mycobacterium senegalense, NCTC 10956, strain IEMVT 378
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