STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLO52886.1NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Nudix hydrolase family. (239 aa)    
Predicted Functional Partners:
KLO52885.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.699
cya_2
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
 
  0.648
nadR
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.642
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.604
metH_1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.594
cinA
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
    
  0.591
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
  0.589
fumA
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.580
ribBA_1
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.573
KLO48664.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.548
Your Current Organism:
Mycolicibacterium senegalense
NCBI taxonomy Id: 1796
Other names: ATCC 35796, CCUG 21001, CIP 104941, DSM 43656, JCM 15467, Mycobacterium farcinogenes subsp. senegalense, Mycobacterium senegalense, NCTC 10956, strain IEMVT 378
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