STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLO53255.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)    
Predicted Functional Partners:
cspA_2
Cold-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.773
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.692
cfp6
Low molecular weight protein antigen 6; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.659
espR
Secretion protein EspR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.653
KLO54035.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.646
KLO48268.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.629
KLO54553.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.621
KLO50874.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.620
KLO53796.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.608
KLO52288.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.597
Your Current Organism:
Mycolicibacterium senegalense
NCBI taxonomy Id: 1796
Other names: ATCC 35796, CCUG 21001, CIP 104941, DSM 43656, JCM 15467, Mycobacterium farcinogenes subsp. senegalense, Mycobacterium senegalense, NCTC 10956, strain IEMVT 378
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.