STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemN_1Oxygen-independent coproporphyrinogen-III oxidase 1. (463 aa)    
Predicted Functional Partners:
CZF82039.1
ChuX-like family protein.
  
 0.954
CZF82041.1
Pyridoxamine 5'-phosphate oxidase.
 
   
 0.839
CZF82032.1
Biopolymer transport protein ExbD/TolR.
 
     0.748
hxuC
Heme/hemopexin utilization protein C precursor.
 
   
 0.738
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.716
ompW_1
Outer membrane protein W precursor.
  
  
 0.711
ompW_2
Outer membrane protein W precursor.
  
  
 0.711
CZF82036.1
Transport protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
   
 0.697
hemN_2
Oxygen-independent coproporphyrinogen-III oxidase 1; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
0.694
hemF
Coproporphyrinogen-III oxidase, aerobic; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
    
 0.693
Your Current Organism:
Grimontia celer
NCBI taxonomy Id: 1796497
Other names: CECT 9029, G. celer, Grimontia celer Pujalte et al. 2016, Grimontia sp. 96-237, KCTC 42960, LMG 29238, LMG:29238, strain 96-237
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