node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A4V02_02385 | A4V02_11075 | A4V02_02385 | A4V02_11075 | Threonine ammonia-lyase. | Serine acetyltransferase. | 0.814 |
A4V02_02385 | glyA | A4V02_02385 | A4V02_11485 | Threonine ammonia-lyase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.930 |
A4V02_02385 | pssA | A4V02_02385 | A4V02_12725 | Threonine ammonia-lyase. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
A4V02_02385 | serB | A4V02_02385 | A4V02_02980 | Threonine ammonia-lyase. | Phosphoserine phosphatase SerB. | 0.916 |
A4V02_02385 | trpA | A4V02_02385 | A4V02_01705 | Threonine ammonia-lyase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.921 |
A4V02_02385 | trpB | A4V02_02385 | A4V02_00435 | Threonine ammonia-lyase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.905 |
A4V02_02385 | trpB-2 | A4V02_02385 | A4V02_01675 | Threonine ammonia-lyase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.937 |
A4V02_02985 | serB | A4V02_02985 | A4V02_02980 | PNPLA domain-containing protein. | Phosphoserine phosphatase SerB. | 0.802 |
A4V02_11075 | A4V02_02385 | A4V02_11075 | A4V02_02385 | Serine acetyltransferase. | Threonine ammonia-lyase. | 0.814 |
A4V02_11075 | glyA | A4V02_11075 | A4V02_11485 | Serine acetyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.836 |
A4V02_11075 | pssA | A4V02_11075 | A4V02_12725 | Serine acetyltransferase. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.801 |
A4V02_11075 | serB | A4V02_11075 | A4V02_02980 | Serine acetyltransferase. | Phosphoserine phosphatase SerB. | 0.863 |
A4V02_11075 | trpA | A4V02_11075 | A4V02_01705 | Serine acetyltransferase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.812 |
A4V02_11075 | trpB | A4V02_11075 | A4V02_00435 | Serine acetyltransferase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.800 |
A4V02_11075 | trpB-2 | A4V02_11075 | A4V02_01675 | Serine acetyltransferase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.811 |
glyA | A4V02_02385 | A4V02_11485 | A4V02_02385 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Threonine ammonia-lyase. | 0.930 |
glyA | A4V02_11075 | A4V02_11485 | A4V02_11075 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Serine acetyltransferase. | 0.836 |
glyA | pssA | A4V02_11485 | A4V02_12725 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
glyA | serB | A4V02_11485 | A4V02_02980 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase SerB. | 0.940 |
glyA | serC | A4V02_11485 | A4V02_07560 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.551 |