STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A4V02_08065Carboxynorspermidine decarboxylase. (383 aa)    
Predicted Functional Partners:
A4V02_11825
Saccharopine dehydrogenase.
 
  
 0.813
A4V02_08070
DNA helicase.
       0.672
A4V02_08075
23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
       0.645
A4V02_08060
Glycosyl transferase family 2.
       0.596
A4V02_08055
MPN domain-containing protein; Belongs to the UPF0758 family.
       0.572
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.568
A4V02_08080
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
       0.525
A4V02_08090
Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
   
   0.497
A4V02_08095
DNA polymerase III subunit epsilon.
  
    0.469
A4V02_08100
Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication a [...]
  
    0.458
Your Current Organism:
Muribaculum intestinale
NCBI taxonomy Id: 1796646
Other names: DSM 28989, KCTC 15537, M. intestinale, Muribaculaceae bacterium DSM 100739, Muribaculaceae bacterium DSM 100746, Muribaculum intestinale Lagkouvardos et al. 2016, Parabacteroides sp. YL27, Porphyromonadaceae bacterium YL27, strain YL27
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.