STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkAATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (326 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.965
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
   
  
 0.929
A4V02_09805
Fructose-1,6-bisphosphate aldolase, class II.
  
 
 0.927
A4V02_00245
Transketolase; Belongs to the transketolase family.
  
 
 0.917
fbp
Fructose-1,6-bisphosphatase class 3.
     
 0.910
A4V02_09735
Mannose-6-phosphate isomerase.
     
 0.908
A4V02_07610
Carbohydrate kinase.
  
 
 0.907
pfp
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 
0.900
A4V02_12710
Uncharacterized protein.
    
  0.848
A4V02_09970
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 0.756
Your Current Organism:
Muribaculum intestinale
NCBI taxonomy Id: 1796646
Other names: DSM 28989, KCTC 15537, M. intestinale, Muribaculaceae bacterium DSM 100739, Muribaculaceae bacterium DSM 100746, Muribaculum intestinale Lagkouvardos et al. 2016, Parabacteroides sp. YL27, Porphyromonadaceae bacterium YL27, strain YL27
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