HhoB_2 protein (Mycolicibacterium thermoresistibile)

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HhoB_2

Trypsin-like serine protease with C-terminal PDZ domain. (343 aa)

Predicted Functional Partners:

HhoB_1

0.928

DegP

0.926

glpK

0.668

arc

0.659

Mec

0.634

Pks2

0.616

PpsA_2

0.615

RMCT_4559

0.614

RMCT_0044

0.613

KatA

0.608

Your Current Organism:

Mycolicibacterium thermoresistibile

NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DegP	HhoB_1	RMCT_2836	RMCT_1683	Trypsin-like serine protease with C-terminal PDZ domain.	Peptidase S1 and S6, chymotrypsin/Hap.	0.923
DegP	HhoB_2	RMCT_2836	RMCT_0045	Trypsin-like serine protease with C-terminal PDZ domain.	Trypsin-like serine protease with C-terminal PDZ domain.	0.926
DegP	KatA	RMCT_2836	RMCT_0066	Trypsin-like serine protease with C-terminal PDZ domain.	Catalase.	0.608
DegP	Mec	RMCT_2836	RMCT_2193	Trypsin-like serine protease with C-terminal PDZ domain.	Mov34/MPN/PAD-1 family protein.	0.634
DegP	Pks2	RMCT_2836	RMCT_4379	Trypsin-like serine protease with C-terminal PDZ domain.	Polyketide synthase pks5.	0.616
DegP	PpsA_2	RMCT_2836	RMCT_0416	Trypsin-like serine protease with C-terminal PDZ domain.	Beta-ketoacyl synthase.	0.615
DegP	RMCT_4559	RMCT_2836	RMCT_4559	Trypsin-like serine protease with C-terminal PDZ domain.	Stage II sporulation protein E.	0.614
DegP	arc	RMCT_2836	RMCT_4326	Trypsin-like serine protease with C-terminal PDZ domain.	ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.659
DegP	glpK	RMCT_2836	RMCT_0079	Trypsin-like serine protease with C-terminal PDZ domain.	Glycerol kinase GlpK; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.	0.668
HhoB_1	DegP	RMCT_1683	RMCT_2836	Peptidase S1 and S6, chymotrypsin/Hap.	Trypsin-like serine protease with C-terminal PDZ domain.	0.923
HhoB_1	HhoB_2	RMCT_1683	RMCT_0045	Peptidase S1 and S6, chymotrypsin/Hap.	Trypsin-like serine protease with C-terminal PDZ domain.	0.928
HhoB_1	KatA	RMCT_1683	RMCT_0066	Peptidase S1 and S6, chymotrypsin/Hap.	Catalase.	0.608
HhoB_1	Mec	RMCT_1683	RMCT_2193	Peptidase S1 and S6, chymotrypsin/Hap.	Mov34/MPN/PAD-1 family protein.	0.634
HhoB_1	Pks2	RMCT_1683	RMCT_4379	Peptidase S1 and S6, chymotrypsin/Hap.	Polyketide synthase pks5.	0.616
HhoB_1	PpsA_2	RMCT_1683	RMCT_0416	Peptidase S1 and S6, chymotrypsin/Hap.	Beta-ketoacyl synthase.	0.615
HhoB_1	RMCT_4559	RMCT_1683	RMCT_4559	Peptidase S1 and S6, chymotrypsin/Hap.	Stage II sporulation protein E.	0.614
HhoB_1	arc	RMCT_1683	RMCT_4326	Peptidase S1 and S6, chymotrypsin/Hap.	ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.	0.659
HhoB_1	glpK	RMCT_1683	RMCT_0079	Peptidase S1 and S6, chymotrypsin/Hap.	Glycerol kinase GlpK; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.	0.668
HhoB_2	DegP	RMCT_0045	RMCT_2836	Trypsin-like serine protease with C-terminal PDZ domain.	Trypsin-like serine protease with C-terminal PDZ domain.	0.926
HhoB_2	HhoB_1	RMCT_0045	RMCT_1683	Trypsin-like serine protease with C-terminal PDZ domain.	Peptidase S1 and S6, chymotrypsin/Hap.	0.928

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