STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpKGlycerol kinase GlpK; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (510 aa)    
Predicted Functional Partners:
GlpD_1
Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
 0.998
arc
ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
 0.986
GlpD_2
Glycerol-3-phosphate dehydrogenase glpD1; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
 0.984
Mec
Mov34/MPN/PAD-1 family protein.
   
 0.982
PlsB
Glycerol-3-phosphate acyltransferase; Belongs to the GPAT/DAPAT family.
    
 0.926
AdhC2
NADP-dependent alcohol dehydrogenase C.
    
 0.924
YutF
Phosphatase.
  
 
 0.919
AqpZ2
Glycerol uptake facilitator; Belongs to the MIP/aquaporin (TC 1.A.8) family.
  
 
 0.907
RMCT_3355
20S proteasome, A and B subunits.
   
 0.887
prcB
Proteasome beta subunit prcB; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
   
 0.887
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.