Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AcnAAconitate hydratase. (948 aa)    
Predicted Functional Partners:
GltA2
Type II citrate synthase; Belongs to the citrate synthase family.
 
 0.997
CitA
Citrate synthase 2; Belongs to the citrate synthase family.
 
 0.997
Kgd
Alpha-ketoglutarate decarboxylase.
 
 0.979
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
 0.958
Icd2
Isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family.
  
 
 0.951
AceA
Isocitrate lyase icl.
  
 
 0.938
PrpD
2-methylcitrate dehydratase.
  
 
 0.938
Icl
Isocitrate lyase aceAb.
  
 
 0.924
rpmF
50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
  
 0.895
atpA
F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
  
 0.893
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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