Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Cph1Two-component system sensor kinase. (546 aa)    
Predicted Functional Partners:
AfsQ1
Response regulator receiver modulated serine phosphatase.
 
  
 0.978
RMCT_4559
Stage II sporulation protein E.
 
 
 0.963
Rcp1
Response regulator receiver protein.
 
   
 0.961
Cya_1
Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
     
 0.821
AdrA
Diguanylate cyclase.
  
  
 0.817
RMCT_1692
Putative uncharacterized protein.
 
  
 0.783
Gmr
GAF sensor-containing diguanylate cyclase/phosphodiesterase.
  
  
 0.741
Bfr
Bacterioferritin bfrA; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family.
  
  
 0.708
CdsA
Membrane phosphatidate cytidylyltransferase cdsA; Belongs to the CDS family.
   
    0.692
RMCT_0290
Anti-sigma regulatory factor.
 
  
 0.687
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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