Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BioYBioY protein. (216 aa)    
Predicted Functional Partners:
BioN
Cobalt transport protein.
 
 0.998
BioM
Cobalt ABC transporter ATPase.
 
  
 0.991
EcfT
Cobalt transport protein.
 
 0.964
EcfA1
Cobalt ABC transporter ATPase subunit; Part of an ABC transporter complex. Responsible for energy coupling to the transport system.
   
 
 0.884
CbiQ
Cobalt ABC transporter, inner membrane subunit C biQ.
  
 
 0.797
AccD3
acetyl-CoA carboxylase carboxyl transferase beta subunit accD3.
 
   
 0.648
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
  
 0.618
bioD
Dithiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
  
 0.593
FklB
Peptidyl-prolyl cis-trans isomerase domain-containing protein.
       0.559
KasA_2
Fatty acid synthase.
     
 0.545
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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