Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SigMSigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (174 aa)    
Predicted Functional Partners:
RMCT_0422
Glyoxalase/bleomycin resistance protein/dioxygenase.
 
    0.850
EthR_1
Transcriptional regulator.
     
 0.752
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.674
RMCT_2330
Anti-sigma factor.
  
 
 0.562
MoaA_1
Radical SAM peptide maturase, mycofactocin system.
  
  
 0.560
RMCT_0425
Mycofactocin system RPExFGAL protein.
  
  
 0.550
RMCT_2837
RNA polymerase sigma-70 factor.
  
 
 0.518
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 
 0.508
RMCT_4472
Putative uncharacterized protein.
  
  
 0.477
RpoE_3
RNA polymerase sigma factor SigE; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.467
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.