Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Pkn1Sulfatase-modifying factor 1. (300 aa)    
Predicted Functional Partners:
AtsA
Arylsulfatase atsA.
 
   0.954
BetC
Hydrolase.
 
   0.900
AtsA_1
Arylsulfatase AtsA.
 
   0.763
egtD
S-adenosyl-L-methionine- dependentmethyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
 
  
 0.740
egtA
Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.
  
  
 0.586
YcjS
Oxidoreductase domain-containing protein.
 
    0.506
RMCT_0772
lysine-N-oxygenase mbtG.
  
  
 0.498
egtC
TIGR03442 family protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.
  
  
 0.491
PknF_3
Serine/threonine protein kinase.
 
  
 0.489
RMCT_1441
Sulfatase family protein.
  
   0.473
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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