| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Adh_1 | AroG_1 | RMCT_0567 | RMCT_0568 | Alcohol dehydrogenase GroES domain-containing protein. | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.490 |
| AroG_1 | Adh_1 | RMCT_0568 | RMCT_0567 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Alcohol dehydrogenase GroES domain-containing protein. | 0.490 |
| AroG_1 | AroG_2 | RMCT_0568 | RMCT_3895 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase aroG; Belongs to the class-II DAHP synthase family. | 0.913 |
| AroG_1 | RMCT_1677 | RMCT_0568 | RMCT_1677 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Chorismate mutase. | 0.576 |
| AroG_1 | TyrC | RMCT_0568 | RMCT_0032 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Prephenate dehydrogenase. | 0.833 |
| AroG_1 | aroB | RMCT_0568 | RMCT_3677 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.985 |
| AroG_1 | aroC | RMCT_0568 | RMCT_3679 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.487 |
| AroG_1 | aroE | RMCT_0568 | RMCT_3683 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Shikimate 5-dehydrogenase. | 0.707 |
| AroG_1 | aroK | RMCT_0568 | RMCT_3678 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.672 |
| AroG_1 | pheA | RMCT_0568 | RMCT_3494 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Prephenate dehydratase. | 0.807 |
| AroG_1 | trpE | RMCT_0568 | RMCT_4430 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.471 |
| AroG_2 | AroG_1 | RMCT_3895 | RMCT_0568 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase aroG; Belongs to the class-II DAHP synthase family. | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.913 |
| AroG_2 | RMCT_1677 | RMCT_3895 | RMCT_1677 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase aroG; Belongs to the class-II DAHP synthase family. | Chorismate mutase. | 0.991 |
| AroG_2 | aroB | RMCT_3895 | RMCT_3677 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase aroG; Belongs to the class-II DAHP synthase family. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.984 |
| AroG_2 | aroC | RMCT_3895 | RMCT_3679 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase aroG; Belongs to the class-II DAHP synthase family. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.508 |
| AroG_2 | aroE | RMCT_3895 | RMCT_3683 | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase aroG; Belongs to the class-II DAHP synthase family. | Shikimate 5-dehydrogenase. | 0.593 |
| RMCT_1677 | AroG_1 | RMCT_1677 | RMCT_0568 | Chorismate mutase. | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.576 |
| RMCT_1677 | AroG_2 | RMCT_1677 | RMCT_3895 | Chorismate mutase. | 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase aroG; Belongs to the class-II DAHP synthase family. | 0.991 |
| RMCT_1677 | TyrC | RMCT_1677 | RMCT_0032 | Chorismate mutase. | Prephenate dehydrogenase. | 0.965 |
| RMCT_1677 | aroB | RMCT_1677 | RMCT_3677 | Chorismate mutase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.419 |