Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HsaA_2Pigment production hydroxylase. (387 aa)    
Predicted Functional Partners:
FadJ
3-hydroxyacyl-CoA dehydrogenase.
  
 0.787
FadB2
3-hydroxybutyryl-CoA dehydrogenase fadB2.
  
 0.721
BphI
4-hydroxy-2-ketovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 0.688
FcbB2_1
enoyl-CoA hydratase/isomerase.
 
 0.677
FcbB2_3
enoyl-CoA hydratase/carnithine racemase.
 
 0.669
FcbB2_5
enoyl-CoA hydratase/carnithine racemase.
 
 0.663
KasA_2
Fatty acid synthase.
  
 0.662
EchA8_20
enoyl-CoA hydratase.
 
 0.661
CaiD_11
enoyl-CoA hydratase.
 
 0.660
RibBA_1
3,4-dihydroxy-2-butanone 4-phosphate synthase.
 
     0.658
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
Server load: low (24%) [HD]