Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
Icd2Isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family. (745 aa)    
Predicted Functional Partners:
RMCT_0837
Oxidoreductase subunit alpha.
  
 
 0.982
AcnA
Aconitate hydratase.
  
 
 0.951
Kgd
Alpha-ketoglutarate decarboxylase.
   
 
 0.950
RMCT_0836
2-oxoglutarate ferredoxin oxidoreductase subunit beta.
  
 
 0.948
GltB
Ferredoxin-dependent glutamate synthase, large subunit gltB.
     
 0.926
GdhA
Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.872
PurB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 0.860
GdhB_2
NAD-dependent glutamate dehydrogenase gdh.
   
 
 0.834
GltD
Glutamate synthase subunit beta.
   
 
 0.822
argH
Argininosuccinate lyase.
    
 0.821
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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