sigA protein (Mycolicibacterium thermoresistibile)

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sigA

RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (504 aa)

Predicted Functional Partners:

rpoB

0.992

rpoC

0.987

rpoA

0.984

rbpA

0.980

rpoZ

0.955

RMCT_3339

0.937

whiB-5

0.913

PafC

0.891

HelD

0.890

whiB-6

0.887

Your Current Organism:

Mycolicibacterium thermoresistibile

NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HelD	rbpA	RMCT_1348	RMCT_0189	Helicase.	Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.	0.818
HelD	rpoA	RMCT_1348	RMCT_0527	Helicase.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.825
HelD	rpoB	RMCT_1348	RMCT_2930	Helicase.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.906
HelD	rpoC	RMCT_1348	RMCT_2929	Helicase.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.901
HelD	rpoZ	RMCT_1348	RMCT_3654	Helicase.	DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.858
HelD	sigA	RMCT_1348	RMCT_0691	Helicase.	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.890
PafC	rbpA	RMCT_4337	RMCT_0189	Transcriptional regulator-like protein.	Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.	0.835
PafC	rpoA	RMCT_4337	RMCT_0527	Transcriptional regulator-like protein.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.772
PafC	rpoB	RMCT_4337	RMCT_2930	Transcriptional regulator-like protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.898
PafC	rpoC	RMCT_4337	RMCT_2929	Transcriptional regulator-like protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.783
PafC	rpoZ	RMCT_4337	RMCT_3654	Transcriptional regulator-like protein.	DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.807
PafC	sigA	RMCT_4337	RMCT_0691	Transcriptional regulator-like protein.	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.891
RMCT_3339	rbpA	RMCT_3339	RMCT_0189	Transcription factor.	Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.	0.978
RMCT_3339	rpoA	RMCT_3339	RMCT_0527	Transcription factor.	DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.956
RMCT_3339	rpoB	RMCT_3339	RMCT_2930	Transcription factor.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.980
RMCT_3339	rpoC	RMCT_3339	RMCT_2929	Transcription factor.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.960
RMCT_3339	rpoZ	RMCT_3339	RMCT_3654	Transcription factor.	DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.963
RMCT_3339	sigA	RMCT_3339	RMCT_0691	Transcription factor.	RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.937
RMCT_3339	whiB-6	RMCT_3339	RMCT_2359	Transcription factor.	Transcriptional regulatory protein whib-like whiB7; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.	0.774
rbpA	HelD	RMCT_0189	RMCT_1348	Hypothetical protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.	Helicase.	0.818

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