Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IdeR_2Iron-dependent repressor and activator ideR. (229 aa)    
Predicted Functional Partners:
HrdB
RNA polymerase sigma factor sigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.781
DegQ
Trypsin-like serine protease with C-terminal PDZ domain.
  
    0.670
RMCT_0741
35 kDa alanine rich protein.
  
  
 0.669
MetN_2
ABC-type metal ion transport system, ATPase component; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
   
 
 0.658
MbtB_2
Phenyloxazoline synthase mbtB.
     
 0.645
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
     
 0.632
hemL
Glutamate-1-semialdehyde aminotransferase.
     
 0.631
Fur
Ferric uptake regulation protein furB; Belongs to the Fur family.
  
  
 0.601
RMCT_2686
Type III restriction enzyme, res subunit.
 
     0.590
ResA_1
Alkyl hydroperoxide reductase/Thiol specific antioxidant/Mal allergen.
  
  
 0.570
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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