node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IspD_1 | IspD_2 | RMCT_0947 | RMCT_0948 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase. | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase. | 0.946 |
IspD_1 | RMCT_3339 | RMCT_0947 | RMCT_3339 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase. | Transcription factor. | 0.521 |
IspD_1 | dxr | RMCT_0947 | RMCT_4259 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.987 |
IspD_1 | dxs | RMCT_0947 | RMCT_0675 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.869 |
IspD_1 | ispE | RMCT_0947 | RMCT_1540 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.986 |
IspD_1 | ispF | RMCT_0947 | RMCT_3340 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.996 |
IspD_1 | ispG | RMCT_0947 | RMCT_4261 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.871 |
IspD_1 | ispH | RMCT_0947 | RMCT_1426 | 4-diphosphocytidyl-2-methyl-D-erythritol synthase. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.851 |
IspD_2 | IspD_1 | RMCT_0948 | RMCT_0947 | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase. | 4-diphosphocytidyl-2-methyl-D-erythritol synthase. | 0.946 |
IspD_2 | RMCT_0949 | RMCT_0948 | RMCT_0949 | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase. | Twin-arginine translocation pathway signal. | 0.681 |
IspD_2 | RMCT_0950 | RMCT_0948 | RMCT_0950 | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase. | Putative uncharacterized protein. | 0.681 |
IspD_2 | RMCT_3339 | RMCT_0948 | RMCT_3339 | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase. | Transcription factor. | 0.729 |
IspD_2 | dxr | RMCT_0948 | RMCT_4259 | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.991 |
IspD_2 | dxs | RMCT_0948 | RMCT_0675 | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.932 |
IspD_2 | ispE | RMCT_0948 | RMCT_1540 | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.989 |
IspD_2 | ispF | RMCT_0948 | RMCT_3340 | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase. | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.986 |
IspD_2 | ispG | RMCT_0948 | RMCT_4261 | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.903 |
IspD_2 | ispH | RMCT_0948 | RMCT_1426 | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.926 |
RMCT_0949 | IspD_2 | RMCT_0949 | RMCT_0948 | Twin-arginine translocation pathway signal. | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase. | 0.681 |
RMCT_0949 | RMCT_0950 | RMCT_0949 | RMCT_0950 | Twin-arginine translocation pathway signal. | Putative uncharacterized protein. | 0.944 |