Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TrxBThioredoxin reductase. (325 aa)    
Predicted Functional Partners:
TrxA
Thioredoxin; Belongs to the thioredoxin family.
 
 0.998
TrxC
Thioredoxin; Belongs to the thioredoxin family.
 
 0.988
SufS
Cysteine desulfurase csd; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
 
 
  0.927
MdeA_2
Cys/Met metabolism pyridoxal-phosphate-dependent enzyme.
  
 
 0.918
YbbN
Thioredoxin.
  
 
 0.810
RMCT_2079
Alkyl hydroperoxide reductase C protein ahpC.
  
 
 0.758
RMCT_4327
3-Cys thioredoxin peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.758
LytC
Hydrolase.
  
  
 0.657
RpoE_4
RNA polymerase sigma factor SigM; Belongs to the sigma-70 factor family. ECF subfamily.
     
 0.645
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
 
  
 0.620
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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