Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PfkB_2Ribokinase-like domain-containing protein. (331 aa)    
Predicted Functional Partners:
PfkB_1
6-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
  
  
 
0.928
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
  
  
 0.924
GlpX
Fructose 1,6-bisphosphatase II.
    
 0.909
Fda
Fructose-bisphosphate aldolase.
     
  0.900
GlpR
DeoR family transcriptional regulator.
 
  
 0.814
SurE
Survival protein SurE.
 
     0.792
NarK2
Nitrate/nitrite transporter narK2.
  
  
 0.701
RMCT_1443
Nitroreductase.
  
  
 0.679
RMCT_2088
Hypothetical protein.
   
  
 0.671
RMCT_1181
Putative uncharacterized protein.
       0.596
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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