Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RMCT_1222Alpha/beta hydrolase fold protein. (329 aa)    
Predicted Functional Partners:
Pks2
Polyketide synthase pks5.
 
 0.628
PpsA_2
Beta-ketoacyl synthase.
  
 0.587
RMCT_2088
Hypothetical protein.
  
 
 0.548
EryA_1
Acyl transferase domain-containing protein.
  
 0.528
RMCT_4084
FAD dependent oxidoreductase.
 
 
 0.525
CatD_1
Alpha/beta hydrolase fold protein.
  
     0.497
FabG_3
Short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  0.495
HhoB_1
Peptidase S1 and S6, chymotrypsin/Hap.
 
  
 0.494
Sdh_2
Short-chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  0.493
lon
ATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
 
 0.488
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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