node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cbs | MdeA_1 | RMCT_1478 | RMCT_0623 | Cystathionine beta-synthase CBS. | O-acetylhomoserine aminocarboxypropyltransferase. | 0.947 |
Cbs | MdeA_2 | RMCT_1478 | RMCT_3526 | Cystathionine beta-synthase CBS. | Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. | 0.994 |
Cbs | MetH | RMCT_1478 | RMCT_3940 | Cystathionine beta-synthase CBS. | 5-methyltetrahydrofolate-homocystein methyltransferase metH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.947 |
Cbs | PatB | RMCT_1478 | RMCT_1167 | Cystathionine beta-synthase CBS. | Aminotransferase. | 0.916 |
Cbs | ahcY | RMCT_1478 | RMCT_2301 | Cystathionine beta-synthase CBS. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.943 |
Cbs | metB | RMCT_1478 | RMCT_1475 | Cystathionine beta-synthase CBS. | Cystathionine gamma-synthase. | 0.992 |
Cbs | metE | RMCT_1478 | RMCT_1317 | Cystathionine beta-synthase CBS. | 5- methyltetrahydropteroyltriglutamate/ homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.931 |
Cbs | metK | RMCT_1478 | RMCT_3652 | Cystathionine beta-synthase CBS. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.457 |
Cbs | metZ | RMCT_1478 | RMCT_2750 | Cystathionine beta-synthase CBS. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.987 |
MdeA_1 | Cbs | RMCT_0623 | RMCT_1478 | O-acetylhomoserine aminocarboxypropyltransferase. | Cystathionine beta-synthase CBS. | 0.947 |
MdeA_1 | MdeA_2 | RMCT_0623 | RMCT_3526 | O-acetylhomoserine aminocarboxypropyltransferase. | Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. | 0.902 |
MdeA_1 | MetH | RMCT_0623 | RMCT_3940 | O-acetylhomoserine aminocarboxypropyltransferase. | 5-methyltetrahydrofolate-homocystein methyltransferase metH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.976 |
MdeA_1 | PatB | RMCT_0623 | RMCT_1167 | O-acetylhomoserine aminocarboxypropyltransferase. | Aminotransferase. | 0.931 |
MdeA_1 | ahcY | RMCT_0623 | RMCT_2301 | O-acetylhomoserine aminocarboxypropyltransferase. | S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.917 |
MdeA_1 | metB | RMCT_0623 | RMCT_1475 | O-acetylhomoserine aminocarboxypropyltransferase. | Cystathionine gamma-synthase. | 0.945 |
MdeA_1 | metE | RMCT_0623 | RMCT_1317 | O-acetylhomoserine aminocarboxypropyltransferase. | 5- methyltetrahydropteroyltriglutamate/ homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.957 |
MdeA_1 | metK | RMCT_0623 | RMCT_3652 | O-acetylhomoserine aminocarboxypropyltransferase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.516 |
MdeA_1 | metZ | RMCT_0623 | RMCT_2750 | O-acetylhomoserine aminocarboxypropyltransferase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.946 |
MdeA_2 | Cbs | RMCT_3526 | RMCT_1478 | Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. | Cystathionine beta-synthase CBS. | 0.994 |
MdeA_2 | MdeA_1 | RMCT_3526 | RMCT_0623 | Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. | O-acetylhomoserine aminocarboxypropyltransferase. | 0.902 |