Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DevSGAF sensor signal transduction histidine kinase. (584 aa)    
Predicted Functional Partners:
DevR_2
Two component LuxR family transcriptional regulator.
 
 0.999
RMCT_4221
Putative uncharacterized protein.
 
  
 0.936
RMCT_4559
Stage II sporulation protein E.
  
 
 0.923
Acg
Putative uncharacterized protein.
 
   
 0.890
NreC_2
Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
 
 0.873
NreC_3
Two-component system response regulator.
 
 
 0.848
Cya_1
Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
 
 0.795
VraR
Two-component system, regulatory protein.
 
 
 0.733
DevR_1
Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  
 
 0.729
RMCT_4294
Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
  
 
 0.729
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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