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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
AcsA_3acyl-CoA synthetase/AMP-acid ligase. (623 aa)    
Predicted Functional Partners:
Pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.932
MmsA
Methylmalonate-semialdehyde dehydrogenase.
  
 0.931
AccD5_1
propionyl-CoA carboxylase beta subunit 5 accD5.
  
 0.928
AccD6
propionyl-CoA carboxylase beta subunit 6 accD6.
  
 0.928
AccC_2
Bifunctional protein acetyl-/propionyl-coenzyme A carboxylase alpha subunit accA3: biotin carboxylase + biotin carboxyl carrier protein.
  
 0.926
RMCT_3765
acyl-CoA oxidase.
  
 
 0.920
YhfP
Alcohol dehydrogenase, zinc-binding protein.
  
 
 0.918
BkdB
Branched-chain alpha-keto acid dehydrogenase subunit E2.
  
 
 0.914
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 
0.909
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.908
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
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