Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FecIECF subfamily RNA polymerase sigma-24 factor; Belongs to the sigma-70 factor family. (306 aa)    
Predicted Functional Partners:
YjlD_2
NADH dehydrogenase, FAD-containing subunit.
     
 0.800
RMCT_1551
FAD-dependent pyridine nucleotide-disulfide oxidoreductase.
     
 0.800
RMCT_1552
ECF subfamily RNA polymerase sigma-24 factor; Belongs to the sigma-70 factor family.
 
    
0.788
YybR
HxlR family transcriptional regulator.
  
    0.711
IdeR_1
Transcriptional repressor sirR.
  
  
 0.680
RMCT_1346
Alkylhydroperoxidase AhpD core domain-containing protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
  
 0.670
CysL
LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
   
  
 0.654
RMCT_2330
Anti-sigma factor.
  
 
 0.563
YvdT_1
TetR family transcriptional regulator.
  
  
 0.560
GdhA
Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.557
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
Server load: low (16%) [HD]