Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AcoBPyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit. (673 aa)    
Predicted Functional Partners:
BkdB
Branched-chain alpha-keto acid dehydrogenase subunit E2.
 
 0.999
Kgd
Alpha-ketoglutarate decarboxylase.
 
 0.999
RMCT_1636
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component.
 
 0.998
Lpd
Dihydrolipoamide dehydrogenase.
 
 0.998
DlaT
Dihydrolipoamide acetyltransferase.
 
 0.998
PdhA
Pyruvate dehydrogenase E1 component alpha subunit pdhA.
 
0.997
PdhB
Pyruvate dehydrogenase E1 component beta subunit pdhB.
 
0.995
MerA
Mercuric reductase.
 
 0.982
LpdA
Flavoprotein disulfide reductase.
 
 0.980
Mtr
NADPH-dependent mycothiol reductase mtr.
 
 0.975
Your Current Organism:
Mycolicibacterium thermoresistibile
NCBI taxonomy Id: 1797
Other names: ATCC 19527, CCUG 28008, CCUG 41353, CIP 105390, DSM 44167, JCM 6362, M. thermoresistibile, Mycobacterium thermoresistibile, NCTC 10409
Server load: low (18%) [HD]